Evolution in Liver trauma management: A single centre experience.
Paulien BonnyConstantijn BogaertLuís Filipe AbreudeCarvalhoFilip GryspeerdtHasan EkerLaurens HermieFrederik BerrevoetPublished in: Acta chirurgica Belgica (2024)
OBJECTIVESLiver trauma is common and can be treated non-operatively, through radiological embolisation, or surgically. Non-operative management (NOM) is preferred when possible, but specific criteria remain unclear. This retrospective study at a level I trauma centre assessed the evolution and outcomes of liver injury management over more than 20 years.METHODSData from January 1996 to June 2020 were analysed for liver trauma cases. Variables were evaluated, including the type of injury, diagnostic modalities, liver injury grade, transfer from other hospitals, treatment type and length of hospital stay. Outcomes were assessed using soft (hospitalisation time and intensive care unit stay) and hard (mortality) endpoints.RESULTSIn total 406 patients were analysed, of which 375 (92.4%) had a blunt and 31 (7.6%) a penetrating liver trauma. Approximately one-third (31.2%) were hemodynamically unstable, although 78.8% had low-grade liver lesions. The initial treatment was non-operative in 72.9% of the patients (68.5% conservative, 4.4% interventional radiology). Blunt trauma was treated by surgery in 23.2% of the patients, while 74.2% in case of penetrating trauma. Overall mortality was 11.1% including death caused by associated lesions. The 24-hour mortality was 5.7%. Indication for surgical treatment was determined by hemodynamic instability, high grade liver lesion, penetrating trauma and associated lesions.CONCLUSIONSAlthough the role of surgery in liver trauma management has strongly diminished over recent decades, hemodynamically unstable patients, high-grade lesions, penetrating trauma and severe associated lesions are the main indications for surgery. In other situations, NOM by full conservative therapy or radiological embolisation seems effective.
Keyphrases
- high grade
- end stage renal disease
- liver injury
- low grade
- trauma patients
- newly diagnosed
- ejection fraction
- intensive care unit
- chronic kidney disease
- drug induced
- minimally invasive
- healthcare
- blood pressure
- mesenchymal stem cells
- type diabetes
- cardiovascular events
- cardiovascular disease
- bone marrow
- adipose tissue
- metabolic syndrome
- atrial fibrillation
- weight loss
- percutaneous coronary intervention
- insulin resistance
- combination therapy