Human Synovia Contains Trefoil Factor Family (TFF) Peptides 1-3 Although Synovial Membrane Only Produces TFF3: Implications in Osteoarthritis and Rheumatoid Arthritis.
Judith PoppMartin SchichtFabian GarreisPatricia KlingerKolja GelseStefan SesselmannMichael TsokosSaskia EtzoldDankwart StillerHorst ClaassenFriedrich PaulsenPublished in: International journal of molecular sciences (2019)
The data demonstrate the production of TFF3 in SM. Unexpectedly, SF contains all three known TFF peptides. As neither articular cartilage nor SM produce TFF1 and TFF2, we speculate that these originate with high probability from blood serum.