Homologous Recombination Abnormalities Associated With BRCA1/2 Mutations as Predicted by Machine Learning of Targeted Next-Generation Sequencing Data.
Maher AlbitarHong ZhangAndrew PecoraStanley WaintraubDeena GrahamMira HellmannDonna McNamaraAhmad CharifaIvan De DiosWanlong MaAndre GoyPublished in: Breast cancer : basic and clinical research (2023)
mutant cases as gold standard, this ML can be used to predict HRD in cancers with mutations in other HRR genes as well as in WT tumors.