Facial hyperalgesia due to direct action of endothelin-1 in the trigeminal ganglion of mice.

Lenyta Oliveira GomesJuliana Geremias ChichorroErika Ivanna ArayaJade de OliveiraGiles Alexander Rae

Published in: The Journal of pharmacy and pharmacology (2018)

ET-1 injection into the TG promotes ETA R/ETB R-mediated facial heat hyperalgesia, and both receptors are clearly implicated in CION-induced hyperalgesia in the murine TG system.

Keyphrases

neuropathic pain
spinal cord
spinal cord injury
soft tissue
high glucose
diabetic rats
high fat diet induced
heat stress
type diabetes
metabolic syndrome
ultrasound guided
skeletal muscle
endothelial cells
insulin resistance