CSPG4 as a target for the specific killing of triple-negative breast cancer cells by a recombinant SNAP-tag-based antibody-auristatin F drug conjugate.

Neelakshi Mungra Fleury Augustin Nsole Biteghe Zaria Malindi Allan M Huysamen Maryam Karaan Natasha S Hardcastle Rubina Bunjun Shivan Chetty Krupa Naran Dirk Lang Wolfgang F Richter Roger Hunter Stefan Barth

Published in: Journal of cancer research and clinical oncology (2023)

This research underscores the applicability of SNAP-tag in the unambiguous generation of homogeneous and pharmaceutically relevant immunoconjugates that could potentially be instrumental in the management of a daunting disease like TNBC.

Keyphrases

breast cancer cells
cancer therapy
cell free
adverse drug
drug delivery
electronic health record