The usability of daytime and night-time heart rate dynamics as digital biomarkers of depression severity.
Sara SiddiRaquel BailónIago Gine-VázquezFaith MatchamFemke LamersSpyridon KontaxisE LaportaE GarciaF LombardiniP AnnasMatthew HotopfBrenda W J H PenninxAlina IvanK M WhiteS DifrancescoP LocatelliJ AguilóM T Peñarrubia-MariaV A NarayanA FolarinD LeightleyNicholas CumminsS VairavanY RanjanA RintalaG de GirolamoSara K SimblettT Wykesnull nullI Myin-GermeysR DobsonJosep-Maria Haronull nullPublished in: Psychological medicine (2023)
Our findings demonstrate that alterations in resting HR during all day and night are associated with depression severity. These findings may provide an early warning of worsening depression symptoms which could allow clinicians to take responsive treatment measures promptly.