A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina.
Christopher A RajkumarMichael J FoleyFiyyaz Ahmed-JushufAlexandra N NowbarFlorentina A SimaderJohn R DaviesPeter D O'KanePeter HaworthHelen RoutledgeTushar KotechaReto GammaGerald CleshamRupert WilliamsJehangir DinSukhjinder S NijjerNick CurzenNeil RupareliaManas SinhaJason N DunguSashiananthan GanesananthanRamzi Y KhamisLal MughalTim KinnairdRicardo PetracoJames C SprattSayan SenJoban SehmiDavid J CollierAfzal SohaibThomas R KeebleGraham D ColeJames P HowardDarrel P FrancisMatthew J Shun-ShinRasha K Al-Lameenull nullPublished in: The New England journal of medicine (2023)
Among patients with stable angina who were receiving little or no antianginal medication and had objective evidence of ischemia, PCI resulted in a lower angina symptom score than a placebo procedure, indicating a better health status with respect to angina. (Funded by the National Institute for Health and Care Research Imperial Biomedical Research Centre and others; ORBITA-2 ClinicalTrials.gov number, NCT03742050.).
Keyphrases
- percutaneous coronary intervention
- coronary artery disease
- st segment elevation myocardial infarction
- acute myocardial infarction
- acute coronary syndrome
- st elevation myocardial infarction
- antiplatelet therapy
- coronary artery bypass grafting
- healthcare
- coronary artery
- quality improvement
- coronary artery bypass
- atrial fibrillation
- double blind
- public health
- palliative care
- mental health
- emergency department
- heart failure
- minimally invasive
- study protocol
- social media
- climate change
- phase iii
- open label
- drug induced