Dengue virus infection induces inflammation and oxidative stress on the heart.
Lucas Miranda KangussuVivian Vasconcelos CostaVania Claudia OlivonCelso Martins Queiroz-JuniorAntônio Nei Santana GondimMarcos Barrouin MeloDaniela ReisNatália NóbregaNatália AraújoMilene Alvarenga RachidRenan Pedra de SouzaCarlos Renato TirapelliRobson Augusto Souza Dos SantosJader Dos Santos CruzMauro Martins TeixeiraDanielle da Glória de SouzaDaniella BonaventuraPublished in: Heart (British Cardiac Society) (2021)
DENV-3 infection induced a marked cardiac dysfunction, which may be associated with inflammation, oxidative stress and electrophysiological changes in the heart. These findings provide new cardiac insights into the mechanisms involved in the pathogenesis triggered by DENV, contributing to the research of new therapeutic targets for clinical practice.