Toxicity Index, Patient-Reported Outcomes, and Early Discontinuation of Endocrine Therapy for Breast Cancer Risk Reduction in NRG Oncology/NSABP B-35.

Norah L HenrySungjin KimRon D Hays Marcio Augusto Diniz Michael Luu Reena S Cecchini Greg YothersAndré RogatkoPatricia A Ganz

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)

Analysis of AEs using the TI yielded important insights into reasons for discontinuation of endocrine therapy that was enhanced by the addition of PRO baseline and treatment-emergent symptoms.

Keyphrases

patient reported outcomes
breast cancer risk
palliative care
combination therapy
sleep quality
replacement therapy
cell therapy
oxide nanoparticles