Pulmonary dose tolerance in hemithorax radiotherapy for Ewing sarcoma of the chest wall: Are we overestimating the risk of radiation pneumonitis?

Akash D ParekhDaniel J Indelicato Bradford S Hoppe Raymond B Mailhot VegaRonny L RotondoJulie A Bradley

Published in: Pediatric blood & cancer (2021)

Existing guidelines may overestimate pneumonitis risk, even among young children receiving multiagent chemotherapy. For children with chest wall Ewing sarcoma and other thoracic malignancies, more data are needed to refine pediatric dose-effect models for pulmonary toxicity.

Keyphrases

pulmonary hypertension
locally advanced
interstitial lung disease
radiation induced
young adults
radiation therapy
spinal cord
oxidative stress
electronic health record
big data
rectal cancer
systemic sclerosis
squamous cell carcinoma
data analysis
chemotherapy induced
oxide nanoparticles