Steroid responsiveness in alcohol-associated hepatitis is linked to glucocorticoid metabolism, mitochondrial repair, and heat shock proteins.

Josiah E HardestyMeghan HawthorneLe DayJeffrey WarnerDennis WarnerMarina GritsenkoAliya AsgharAndrew StolzTimothy MorganCraig McClainJon JacobsIrina A Kirpich

Published in: Hepatology communications (2024)

This study identified hepatic proteomic changes that may predict responsiveness to corticosteroids and mortality in patients with AH.

Keyphrases

heat shock
oxidative stress
heat stress
heat shock protein
cardiovascular events
type diabetes
risk factors
cardiovascular disease
alcohol consumption
coronary artery disease