Correlation of somatostatin receptor PET/CT imaging features and immunohistochemistry in neuroendocrine tumors of the lung: a retrospective observational study.

Vittoria RufiniMargherita LorussoFrediano InzaniTina PasciutoElizabeth Katherine Anna TriumbariLucia Rosalba GrilloFilippo LoccoStefano MargaritoraEdoardo PescarmonaGuido Rindi

Published in: European journal of nuclear medicine and molecular imaging (2022)

This retrospective study showed an overall good agreement between SSTR2-IHC and tumor uptake at SSTR-PET/CT in lung NETs. SSTR-PET/CT SUV<sub>max</sub> values can be used as a parameter of SSTR2 density. Within the limits imposed by the relatively small cohort, our data suggest that SSTR2-IHC may surrogate SSTR-PET/CT in selected lung NET patients for clinical decision making when SSTR-PET/CT is not available.

Keyphrases

pet ct
neuroendocrine tumors
positron emission tomography
decision making

end stage renal disease
ejection fraction
chronic kidney disease

electronic health record
artificial intelligence
big data

mass spectrometry
patient reported outcomes
deep learning