Non-alkaloidal constituents from the genus Aconitum : a review.

Species of the genus Aconitum are widely distributed in the north temperate region and have been used in traditional medicine since antiquity due to their biological activities. Phytochemical investigations of Aconitum species have revealed the presence of multiple active ingredients, including flavonoids, phenylpropanoids, phenolics and acids, terpenoids, and polysaccharides in addition to their diterpenoid alkaloids. These non-alkaloidal constituents show great research significance for their novel structures, broad bioactivities, and chemotaxonomical significance. This review addresses, for the first time, the non-alkaloidal constituents and their biological properties and their taxonomic significance for Aconitum plants to facilitate future research.