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Gasdermin D deficiency attenuates development of ascending aortic dissections in a novel mouse model.

Muhammad J JavedRachael M HowardHua LiLaura CarrascoMarvin L S DirainGang SuGuoshuai CaiGilbert R UpchurchZhihua Jiang
Published in: bioRxiv : the preprint server for biology (2024)
attenuates TAD development, with modulation of cell death and T-cell response likely acting as the underlying mechanism.
Keyphrases
  • cell death
  • mouse model
  • pulmonary artery
  • aortic valve
  • left ventricular
  • cell proliferation
  • pulmonary arterial hypertension
  • cell cycle arrest