Protein expression of close homologue of L1 (CHL1) is a marker for overall survival in non-small cell lung cancer (NSCLC).
Jenny HötzelNathaniel MellingJulia MüllerAdam PolonskiGerrit Wolters-EisfeldJakob R IzbickiKarl-Frederick KarstensMichael TachezyPublished in: Journal of cancer research and clinical oncology (2019)
The prognostic significance of CHL1 makes it a potential prognostic and therapeutic target and underlines its role as a tumour suppressor. Further validation studies and functional analyses are needed to investigate its potential role in tumourigenesis and dissemination.