Efficacy of carbapenem vs non carbapenem β-lactam therapy as empiric antimicrobial therapy in patients with extended-spectrum β-lactamase-producing Enterobacterales urinary septic shock: a propensity-weighted multicenter cohort study.
Erwann CariouRomain GriffierArthur OrieuxStein SilvaStanislas FaguerThierry SeguinSaad NseirEmmanuel CanetArnaud DesclauxBertrand SouweineKada KloucheOlivier GuissetJerome PillotWalter PicardTahar SaghiPierre DelobelDidier GrusonRenaud PrevelAlexandre BoyerPublished in: Annals of intensive care (2023)
In ESBL-E urinary septic shock, empiric treatment with a non carbapenem regimen, including systematically aminoglycosides, was not associated with higher mortality, compared to a carbapenem regimen.
Keyphrases
- septic shock
- klebsiella pneumoniae
- gram negative
- acinetobacter baumannii
- multidrug resistant
- escherichia coli
- drug resistant
- pseudomonas aeruginosa
- staphylococcus aureus
- magnetic resonance
- cardiovascular events
- stem cells
- clinical trial
- urinary tract infection
- type diabetes
- contrast enhanced
- risk factors
- computed tomography
- cell therapy
- cystic fibrosis
- coronary artery disease
- bone marrow
- network analysis
- smoking cessation