Relationship between Pharmacokinetic/Pharmacodynamic Target Attainment and Microbiological Outcome in Critically Ill COVID-19 Patients with Documented Gram-Negative Superinfections Treated with TDM-Guided Continuous-Infusion Meropenem.
Maria Sanz-CodinaMilo GattiCarla TroisiGiacomo FornaroZeno PasquiniFilippo TrapaniAndrea ZanoniFabio CaramelliPierluigi VialeFederico PeaPublished in: Pharmaceutics (2022)
Suboptimal attainment of meropenem PK/PD targets may be a major determinant impacting on microbiological failure in critical COVID-19 patients with Gram-negative superinfections.