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Efficacy and safety of an orally administered DGAT2 inhibitor alone or coadministered with a liver-targeted ACC inhibitor in adults with non-alcoholic steatohepatitis (NASH): rationale and design of the phase II, dose-ranging, dose-finding, randomised, placebo-controlled MIRNA (Metabolic Interventions to Resolve NASH with fibrosis) study.

Neeta B AminAmanda DarekarQuentin M AnsteeVincent Wai-Sun WongFrank TackeManoli VourvahisDouglas S LeeMichael CharltonNaim AlkhouriHirokazu TakahashiCarla Yunis
Published in: BMJ open (2022)
NCT04321031.
Keyphrases
  • phase ii
  • placebo controlled
  • clinical trial
  • open label
  • double blind
  • phase iii
  • study protocol
  • phase ii study
  • physical activity
  • liver injury
  • squamous cell carcinoma
  • cancer therapy
  • drug induced
  • rectal cancer