l-Carnosine Protects Against Deoxynivalenol-Induced Oxidative Stress in Intestinal Stem Cells by Regulating the Keap1/Nrf2 Signaling Pathway.

Jia-Yi ZhouHua-Lin LinYing-Chao QinXiang-Guang LiChun-Qi GaoHui-Chao YanXiu-Qi Wang

Published in: Molecular nutrition & food research (2021)

The study findings unveil that LC potentiates the antioxidant capacity of ISCs by regulating the Keap1/Nrf2 signaling pathway, which contributes to the intestinal epithelial regeneration response to DON insult.

Keyphrases

stem cells
signaling pathway
oxidative stress
pi k akt
epithelial mesenchymal transition
induced apoptosis
protein protein
hydrogen peroxide
mass spectrometry
simultaneous determination
nitric oxide
liquid chromatography