A protein interaction map identifies existing drugs targeting SARS-CoV-2.

Claudia CavaGloria BertoliIsabella Castiglioni

Published in: BMC pharmacology & toxicology (2020)

The integration of drug-gene interactions in the network and molecular docking analysis allows us to obtain several drugs with antiviral activity that, alone or in combination with other treatment options, could be considered as therapeutic approaches against COVID-19.

Keyphrases

sars cov
molecular docking
genome wide
molecular dynamics simulations
respiratory syndrome coronavirus
coronavirus disease
drug induced
copy number
cancer therapy
dna methylation
emergency department
binding protein
protein protein
network analysis
electronic health record