The zebrafish histamine H3 receptor modulates aggression, neural activity and forebrain functional connectivity.

Florian ReichmannNeal RimmerCeinwen A TilleyElisa Dalla VecchiaJoseph PinionAmir Al OustahHector Carreño GutiérrezAndrew M J YoungJonathan R McDearmidMatthew J WinterWilliam H J Norton

Published in: Acta physiologica (Oxford, England) (2020)

These results highlight the importance of zebrafish Hrh3 signalling for aggression and anxiety and uncover the brain areas involved. Targeting this receptor might be a potential novel therapeutic route for human conditions characterized by heightened aggression.

Keyphrases

functional connectivity
resting state
endothelial cells
white matter
binding protein
risk assessment
subarachnoid hemorrhage
brain injury
climate change