Efficient Synthesis of Various Substituted (Thio)Ureas, Semicarbazides, Thiosemicarbazides, Thiazolidones, and Oxadiazole Derived from [2.2]Paracyclophane.
Mohammed B AlshammariAshraf A AlyStefan BräseMartin NiegerLamiaa E Abd El-HaleemPublished in: ACS omega (2022)
The strategies of the syntheses of various (thio)ureas, semicarbazides, thiosemicarbazides, thiazolidones, and oxadiazole derived from the [2.2]paracyclophane molecule are achieved starting with 4-(2.2]paracyclophanyl)isocyanate. The structures of the obtained products were elucidated by NMR, mass spectrometry, and infrared (IR) spectroscopy in addition to high-resolution mass spectrometry (HRMS). X-ray structure analysis was also used to prove the assigned structure.
Keyphrases
- high resolution mass spectrometry
- liquid chromatography
- high resolution
- mass spectrometry
- gas chromatography
- ultra high performance liquid chromatography
- tandem mass spectrometry
- simultaneous determination
- solid state
- magnetic resonance
- capillary electrophoresis
- solid phase extraction
- molecular docking
- single molecule
- magnetic resonance imaging