Time-course mass spectrometry data of adipose mesenchymal stem cells acquiring chondrogenic phenotype.
Jeffrey R JanusStephen G VossBenjamin J MaddenMary Cristine CharlesworthMichael S OldenburgDale EkbomSerban San-MarinaPublished in: BMC research notes (2018)
The data comprise .MGF, .RAW, .MZID, and .XLSX, lists of peaks, peptides and proteins identified by nano-flow liquid chromatography electrospray ionization tandem mass spectrometry analysis upon incubation with non-differentiating (ND) or chondrogenic differentiating (CHD) media (ProteomeXchange ID PXD010236). XLSX files contain the following information: day 1 CT (control, N = 3499 proteins), day 14 ND (N = 3106 proteins), day 28 ND (N = 3116 proteins), day 14 CHD (N = 2901 proteins), and day 28 CHD (N = 2876 proteins). Proteins are characterized with respect to their - 10lgP value, percent coverage, number of total as well as unique peptides after trypsin digestion, derivatization method (carbamidomethylation, oxidation, or combined carbamidomethylation + oxidation), average mass, and include a full description.
Keyphrases
- liquid chromatography
- mass spectrometry
- tandem mass spectrometry
- mesenchymal stem cells
- high performance liquid chromatography
- gas chromatography
- simultaneous determination
- healthcare
- high resolution mass spectrometry
- hydrogen peroxide
- magnetic resonance imaging
- computed tomography
- insulin resistance
- solid phase extraction
- metabolic syndrome
- bone marrow
- artificial intelligence
- liquid chromatography tandem mass spectrometry
- stem cells
- image quality
- skeletal muscle
- cell therapy
- amino acid
- big data
- magnetic resonance