Exploring molecular glioblastoma: Insights from advanced imaging for a nuanced understanding of the molecularly defined malignant biology.
Michael GriessmairClaire DelbridgeJulian ZiegenfeuterKirsten JungTobias MuellerSeverin SchrammDenise BernhardtFriederike Schmidt-GrafOlivia KertelsMarie ThomasClaus ZimmerBernhard MeyerStephanie E CombsIgor YakushevBenedikt WiestlerMarie-Christin MetzPublished in: Neuro-oncology advances (2024)
Quantitative analysis of diffusion and perfusion parameters shows potential in reflecting the malignant tumor biology of molGB. It may increase awareness of molGB in a nonenhancing, "benign" appearing tumor. Our results support the emerging hypothesis that molGB might present glioblastoma captured at an early stage of gliomagenesis.