Engineering a safe monoclonal anti-human IL-2 that is effective in a murine model of food allergy and asthma.
Martin KleinBarbara Misme-AucouturierMarie-Aude CheminantMarion De CarvalhoMarie WautersOlivier TranquetAntoine MagnanGrégory BouchaudPublished in: Allergy (2021)
In conclusion,complexed IL-2/anti-IL-2 may restore Treg numbers and function in respiratory and food allergies, thereby improving allergic markers and symptoms. Our IL-2/anti-IL-2 complex offers new hope for reestablishing immune tolerance in patients with allergies.