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The S1 helix is a VIP in VSP.

Ben Short
Published in: The Journal of general physiology (2024)
JGP study (Rayaprolu et al. https://doi.org/10.1085/jgp.202313467) shows that hydrophobic residues in the S1 transmembrane domain modulate the voltage sensor movements and enzymatic activity of voltage-sensing phosphatase.
Keyphrases
  • dna binding
  • transcription factor