Mesenchymal stem cells prolong survival and prevent lethal complications in a porcine model of fulminant liver failure.

Niang-Cheng LinHao-Hsiang WuJennifer Hui-Chun HoChin-Su LiuOscar Kuang-Sheng Lee

Published in: Xenotransplantation (2019)

Together, MSCs prolong the survival and prevent lethal sequelae of I-R injury-induced FLF by maintenance of liver-function homeostasis and rescue of ROS in the acute stage and by homing and differentiation into hepatocytes in the subacute stage.

Keyphrases

liver failure
mesenchymal stem cells
hepatitis b virus
umbilical cord
free survival
drug induced
liver injury
bone marrow
high glucose
dna damage
cell death
diabetic rats
reactive oxygen species
stem cells
cell therapy
intensive care unit
respiratory failure
aortic dissection