Perineural and Systemic Dexamethasone and Ulnar Nerve Block Duration A Randomized, Blinded, Placebo-controlled Trial in Healthy Volunteers.

Mathias MaagaardEmma R StormholtLasse F NielsenFinn BærentzenJakob DankerJosephine ZachodnikPia JægerOle MathiesenJakob H Andersen

Published in: Anesthesiology (2023)

Perineural dexamethasone as an adjunct to bupivacaine in healthy volunteers resulted in a greater duration of an ulnar nerve block when compared with placebo. Systemic dexamethasone resulted in a similar duration as placebo.

Keyphrases

double blind
high dose
low dose
placebo controlled
study protocol
phase iii
clinical trial
postoperative pain
drug induced
open label
chronic pain