Implementation science in pediatric oncology: A narrative review and future directions.
Charles A PhillipsLamia P BarakatBrad H PollockL Charles BaileyRinad S BeidasPublished in: Pediatric blood & cancer (2022)
Implementation science (IS) has garnered attention within oncology, and most prior IS work has focused on adult, not pediatric, oncology. This narrative review broadly characterizes IS for pediatric oncology. It includes studies through 2020 using the following search terms in PubMed, Ovid Medline, and Cochrane: "implementation science," "pediatric," "childhood," "cancer," and "oncology." Systematic review was not performed due to the limited number of heterogeneous studies. Of 216 articles initially reviewed, nine were selected as specific to IS and pediatric oncology. All nine examined oncologic supportive care, cancer prevention, or cancer control. The supportive care focus is potentially due to the presence of cooperative study groups such as the Children's Oncology Group, which efficiently drive cancer-directed therapy changes through clinical trials. Future IS within pediatric oncology should embrace this ecosystem and focus on cancer control interventions that benefit patients across multiple cancer types and patients treated outside cooperative group studies.
Keyphrases
- childhood cancer
- palliative care
- papillary thyroid
- young adults
- healthcare
- systematic review
- squamous cell
- clinical trial
- primary care
- public health
- quality improvement
- prostate cancer
- end stage renal disease
- squamous cell carcinoma
- lymph node metastasis
- chronic kidney disease
- current status
- newly diagnosed
- ejection fraction
- minimally invasive
- case control
- chronic pain
- peritoneal dialysis
- replacement therapy
- double blind
- phase iii