A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma.

Samender RandhawaJessica PinskerMadhurya AmirapuMetlapalli Venkata Sravanthi Prashanth Ashok KumarKomal Akhtar

Published in: Journal of investigative medicine high impact case reports (2022)

Perivascular epithelioid cell tumors (PEComas) are related to the tuberous sclerosis complex (TSC) and are commonly benign. When malignant, they can be aggressive with local invasion and metastatic spread. Conventional PEComas do not have TFE3 gene rearrangement and are associated with TSC with a preference for an occurrence at a younger age. We report a case of a young male who had progressive chronic hip pain and was found to have a TFE3 -associated PEComa in his pelvic region.

Keyphrases

chronic pain
pain management
neuropathic pain
total hip arthroplasty
squamous cell carcinoma
small cell lung cancer
multiple sclerosis
stem cells
risk assessment
single cell
bone marrow
cell therapy
drug induced
copy number
middle aged
spinal cord
gene expression
dna methylation
postoperative pain