Autoinducer-2 produced by oral microbial flora and alveolar bone loss in periodontitis.

Cheng LiHancheng ZhouHuiqing GouZixin FanYifei ZhangPengzhou TangJiaxin HuangYan XuLu Li

Published in: Journal of periodontal research (2024)

We demonstrated that the AI-2 concentration varied with the alveolar bone destruction in periodontitis, and it may have the potential for screening periodontitis. F. nucleatum AI-2 promoted osteoclast differentiation in a dose-dependent manner and aggravated bone loss.

Keyphrases

bone loss
artificial intelligence
microbial community
machine learning
human health
risk assessment
body composition
soft tissue