In Vitro Inhibitory Effects of Agarwood Tea ( Aquilaria malaccensis Lamk) Aqueous Extract on Human Cytochrome P450 (CYP) Enzyme Activities.

Pan YanUng Yee TzePremika A/P R JagadishLim Kuan HonLamia Noushin Sadeque ChowdhuryShang TaoOng Chin Eng

Published in: Drug metabolism and bioanalysis letters (2022)

These findings can be used to design additional in vitro investigations using clinical relevant drug substrates for CYP2C9, CYP2D6, and CYP3A4. Subsequently, future studies can be conducted to determine potential interactions between agarwood tea aqueous extract and CYP using in vivo models.

Keyphrases

oxidative stress
endothelial cells
ionic liquid
anti inflammatory
current status
emergency department
risk assessment
drug induced