Serum biomarkers of iron stores are associated with worse physical health-related quality of life in nondialysis-dependent chronic kidney disease patients with or without anemia.
Murilo GuedesDaniel MuenzJarcy ZeeMarcelo Barreto LopesSandra WaechterBénédicte StengelZiad A MassyElodie SpeyerCarole AyavFredric FinkelsteinRicardo SessoRonald L PisoniBruce M RobinsonRoberto Pecoits-FilhoPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2021)
Low TSAT levels, as well as both low TSAT with low ferritin and low TSAT with high ferritin, are associated with worse physical HRQoL in NDD-CKD patients, even after accounting for Hb level. Interventional studies of iron therapy on HRQoL among NDD-CKD individuals are needed to confirm these findings.