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Tranexamic Acid Administration Does Not Alter Inflammation After Traumatic Brain Injury, Regardless of Timing.

Matthew R BaucomTaylor E WallenAdam D PriceLisa G EnglandRebecca M SchusterMichael D Goodman
Published in: The Journal of surgical research (2024)
Our results demonstrate that neither early nor delayed administration of TXA conveyed significant systemic or cerebral benefit in cytokine levels following TBI. Further research should be conducted to assess blood brain barrier integrity and neurobehavioral recovery following TXA administration postTBI.
Keyphrases
  • blood brain barrier
  • cerebral ischemia
  • traumatic brain injury
  • oxidative stress
  • subarachnoid hemorrhage
  • brain injury
  • severe traumatic brain injury