Loss of tolerance to glycoprotein 2 isoforms 1 and 4 is associated with Crohn's disease of the pouch.
Donelle CummingsMichael CruiseRocio LopezDirk RoggenbuckVipul JairathYinghong WangBo ShenFlorian RiedersPublished in: Alimentary pharmacology & therapeutics (2018)
The novel anti-GP21 and GP24 antibodies are associated with Crohn's disease of the pouch in ulcerative colitis patients after IPAA. Serological anti-GP2 antibodies could aid in diagnosis of Crohn's disease of the pouch.