Association Between Insulin-Like Growth Factor-1 and Social Cognition in Huntington's Disease.
Cecilia Gil-PoloSaul-Indra Martinez-HortaFrederic SampedroMaría Martín-PalenciaSimón Gundín-MenéndezPilar Alvarez-BañosLaura Maza-PeregSara CalvoCarla CollazoEsther Alonso-GarcíaEsther Riñones-MenaAngela Arrabal-AlonsoJuan Núñez RodriguezMiriam Saiz-RodriguezLaura AguadoNatividad MariscalIgnacio Muñoz-SiscartDolores PiñeiroJessica RivadeneyraMonica Diez-FairenIrene Miguel-PérezEsther Cubo-DelgadoPublished in: Movement disorders clinical practice (2022)
In HD, abnormal IGF-1 function seems to be associated with brain atrophy leading to clinical deficits in social cognition.