Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study.

Nivedithaa DivakaraZac DempseyChitra SaraswatiJohan GarssenDesiree SilvaJeffrey A KeelanClaus T ChristophersenMatthew N CooperSusan L PrescottDebra J PalmerValerie VerhasseltPatricia Macchiaverni

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2024)

This exploratory study shows that prebiotic consumption by lactating mothers selectively alters specific immunomodulatory proteins in HM. This finding is crucial for understanding how prebiotic dietary recommendations for pregnant and lactating women can modify the immune properties of HM and potentially influence infant health outcomes through immune support from breastfeeding.

Keyphrases

human milk
pregnant women
type diabetes
low birth weight
pregnancy outcomes
dairy cows
physical activity
adipose tissue
skeletal muscle
weight loss