Incidence of Post-operative Gastro-esophageal Reflux Disorder in Patients Undergoing Laparoscopic Sleeve Gastrectomy: A Systematic Review and Meta-analysis.
Ander Bengoechea TrujilloDrishti SagarAmoolya Rao AmaravadhiDevika MuraleedharanMuhammad Zauraiz MalikKofi Effa-AbabioMugisha NsengiyumvaTadele TesfayeMaciej WalędziakJoanna Kacperczyk-BartnikPublished in: Obesity surgery (2024)
Gastroesophageal reflux disease (GERD) is a common concern following laparoscopic sleeve gastrectomy (LSG). This paper aimed to assess the incidence of reflux disease following these bariatric procedures. A literature search was conducted to identify observational studies and clinical trials reporting patients developed GERD disease after LSG. Twenty-two studies included in the analysis, involve 20,495 participants, indicated that the estimated proportion of patients who developed post-surgery GERD was 0.35 (95% CI 0.30-0.41). Subgroup analysis revealed a proportion of 0.33 (95% CI 0.27-0.38) in observational studies and 0.58 (95% CI 0.39-0.75) in clinical trials. High heterogeneity was noted across studies (I 2 = 98%). Sensitivity analyses and publication bias assessments were performed to enhance the robustness of the results. Our findings highlight a moderate to high risk of developing GERD following LSG surgery.
Keyphrases
- gastroesophageal reflux disease
- clinical trial
- minimally invasive
- patients undergoing
- coronary artery bypass
- risk factors
- end stage renal disease
- systematic review
- single cell
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- coronary artery disease
- phase iii
- roux en y gastric bypass
- high intensity
- gastric bypass
- phase ii