Associations of NOD2 polymorphisms with Erysipelotrichaceae in stool of in healthy first degree relatives of Crohn's disease subjects.
Williams TurpinLarbi BedraniOsvaldo Espin-GarciaWei XuMark S SilverbergMichelle I SmithJuan Antonio Raygoza GaraySun-Ho LeeDavid S GuttmanAnne GriffithsPaul MoayyediRemo PanaccioneHien HuynhHillary A SteinhartGuy AumaisLevinus A DielemanDan Turnernull nullAndrew D PatersonKenneth CroitoruPublished in: BMC medical genetics (2020)
This result suggests that NOD2 polymorphisms contribute to fecal microbiome composition in asymptomatic individuals. Whether this modulation of the microbiome influences the future development of CD remains to be assessed.
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