Transforming Growth Factor-β1 and Receptor for Advanced Glycation End Products Gene Expression and Protein Levels in Adolescents with Type 1 iabetes Mellitus

Ana Ninic Dragana Bojanin Miron Sopic Marija Mihajlović Jelena Munjas Tatjana Milenković Aleksandra Stefanović Jelena Vekic Vesna Spasojevic-Kalimanovska

Published in: Journal of clinical research in pediatric endocrinology (2020)

Our results indicated gene expression downregulation of TGF-β1 and flRAGE in PBMC of T1D adolescents. TGF-β1 mRNA downregulation may be useful for predicting early elevation of urinary albumin excretion rate.

Keyphrases

transforming growth factor
gene expression
epithelial mesenchymal transition
young adults
signaling pathway
dna methylation
physical activity
cell proliferation
binding protein
amino acid