Reduction of SF 5 CF 3 via iridium catalysis: radical trifluoromethylation of aromatics.
Domenique HerbstrittThomas BraunPublished in: Chemical communications (Cambridge, England) (2023)
The greenhouse gas SF 5 CF 3 acts as CF 3 source for the photocatalytic trifluoromethylation of arenes on using [Ir(dtbbpy)(ppy) 2 ]PF 6 (4,4'-di- tert -butyl-2,2'-dipyridyl, ppy = 2-phenylpyridine) as catalyst. The trifluoromethylation of C 6 D 6 in the presence of 1-octanol results in the concomitant generation of 1-fluorooctane, presumably by intermediate SF 4 .