Oxidation-Reduction Potential in Patients undergoing Transcatheter or Surgical Aortic Valve Replacement.
Kathrin HeldmaierChristian StoppeAndreas GoetzenichAnn-Christina FoldenauerRachat ZayatThomas BreuerGereon SchältePublished in: BioMed research international (2018)
A high preoperative sORP level correlated to more severe illness in the TAVR patients. As the TAVR patients did not show significant differences in their preoperative levels, we assume that there was a smaller production of oxidative agents during TAVR due to the less invasive nature of the procedure. Baseline values and development of antioxidant capacity values strengthen this hypothesis. The significant correlation of pre- and postoperative capacity levels might allow high risk patients to be detected more easily and might provide more adequate and individualized therapy preoperatively. This trial is registered with clinicaltrials.gov, identifier: NCT 02488876.
Keyphrases
- patients undergoing
- end stage renal disease
- ejection fraction
- newly diagnosed
- aortic valve replacement
- aortic stenosis
- aortic valve
- prognostic factors
- peritoneal dialysis
- stem cells
- clinical trial
- transcatheter aortic valve replacement
- heart failure
- study protocol
- coronary artery disease
- nitric oxide
- early onset
- bone marrow
- patient reported