The comparative effectiveness of metformin and risperidone in a rat model of valproic acid-induced autism, Potential role for enhanced autophagy.
Amany Aa AtiaRehab H AshourMarwa Maf ZakiKarawan Ma RahmanNehal M RamadanPublished in: Psychopharmacology (2023)
Our work highlights, for the first time, positive modulation of hippocampus autophagy as potential mechanism underlying improvements in autistic behaviors, observed with metformin, as well as risperidone, therapy.