Neutral Desorption Extractive Electrospray Ionization Mass Spectrometry Analysis Sputum for Non-Invasive Lung Adenocarcinoma Detection.

Qiaoling ZhengJianyong ZhangXinchen WangWenxiong ZhangYipo XiaoSheng HuJianjun Xu

Published in: OncoTargets and therapy (2021)

This study indicates that the application of ND-EESI-MS to sputum analysis can be used as a non-invasive detection of peripheral lung nodules. The use of sputum metabolite biomarkers may aid in the development of a further evaluation program for lung adenocarcinoma.

Keyphrases

mass spectrometry
cystic fibrosis
mycobacterium tuberculosis
pulmonary tuberculosis
multiple sclerosis
high resolution
loop mediated isothermal amplification
ms ms
quality improvement
high performance liquid chromatography
sensitive detection