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Performance of an innovative culture-based digital dipstick for detection of bacteriuria.

Emre IseriSara NilssonAlex van BelkumWouter van der WijngaartVolkan Özenci
Published in: Microbiology spectrum (2023)
In this study, we explore the transformative potential of UTI-lizer, an emerging technology not yet commercially available. Our manuscript shows that UTI-lizer is a promising alternative for detecting the five main pathogens that cause urinary tract infections (UTIs). The results also indicate that digital dipsticks have the potential to uniquely provide UTI diagnostic quality on par with that of gold-standard testing, with the added benefits of ease of testing, rapid test handling time, and simple test equipment. This technology can be helpful in quickly ruling out bacterial infections and reducing the unnecessary use of antibiotics, especially in primary care settings or at the point of care. Moreover, the UTI-lizer test can reduce the number of negative urine samples sent to central laboratories, thus easing the burden of UTI diagnostics on the healthcare system. We believe our study, as well as current and upcoming research based on this technology, is highly relevant for clinical microbiologists, microbiology scientists, general practitioners, and urologists.
Keyphrases
  • urinary tract infection
  • primary care
  • loop mediated isothermal amplification
  • risk factors
  • risk assessment
  • quality improvement
  • human health
  • sensitive detection