Reactive oxygen species enhance rAAV transduction by promoting its escape from late endosomes.

Xiaoping HuangXiao WangYanxuan RenPingzhang GaoWentao XuXiaolan XieYong Diao

Published in: Virology journal (2023)

These data support that ROS generative drugs, such as shikonin, have the potential to promote rAAV vector transduction by promoting rAAV's escape from late endosomes, and enhancing its productive trafficking to the nucleus.

Keyphrases

reactive oxygen species
electronic health record
cell death
big data
machine learning
human health
climate change
drug induced