Timing and choice of systemic anticoagulation in the setting of extremity arterial injury repair.

Dias ArgandykovJefferson A Proaño-ZamudioAnder Dorken-GallastegiAnthony GebranAngela M RenneCharudutt N ParanjapeDavid R KingHaytham M A KaafaraniGeorge C VelmahosJohn O Hwabejire

Published in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2022)

Patients with the operative repair of arterial injuries receiving early perioperative anticoagulation demonstrated an improved limb salvage outcome than those who received late thromboprophylaxis. Our data also suggest that early initiation of prophylaxis may be associated with increased bleeding risk, which may be attenuated using LMWH compared to UFH.

Keyphrases

atrial fibrillation
venous thromboembolism
direct oral anticoagulants
patients undergoing
cardiac surgery
electronic health record
big data
machine learning
acute kidney injury
deep learning
drug induced