Effect of Mineralocorticoid Receptor Antagonism and ACE Inhibition on Angiotensin Profiles in Diabetic Kidney Disease: An Exploratory Study.

Johannes J KovarikChristopher C KalteneckerOliver DomenigMarlies AntlangerMarko PoglitschChantal KopeckyMarcus D Säemann

Published in: Diabetes therapy : research, treatment and education of diabetes and related disorders (2021)

Combined eplerenone and ACEi therapy increases Ang-(1-7) levels in patients with CKD indicating a unique nephroprotective RAAS pattern with considerable therapeutic implications.

Keyphrases

angiotensin ii
angiotensin converting enzyme
chronic kidney disease
type diabetes
wound healing