The Ability of a 3-Gene Host Signature in Blood to Distinguish Tuberculous Meningitis From Other Brain Infections.

Julie HuynhLe Hoang Thanh NhatNguyen Le Hoai BaoHoang Thanh HaiDo Dang Anh ThuTrinh Thi Bich TramVu Thi Mong DungDo Dinh VinhNghiem My NgocJoseph DonovanNguyen Hoan PhuDang Van ThanhNguyen Thi Anh ThuNguyen Duc BangDang Thi Minh HaHo Dang Trung NghiaLe Van TanLe Hong VanGuy ThwaitesNguyen Thuy Thuong Thuong

Published in: The Journal of infectious diseases (2024)

The 3-gene host signature in whole blood has the ability to discriminate TBM from other brain infections, including in individuals with HIV. Validation in large prospective diagnostic study is now required.

Keyphrases

resting state
white matter
copy number
genome wide
antiretroviral therapy
hiv infected
functional connectivity
genome wide identification
hiv positive
hepatitis c virus
human immunodeficiency virus
cerebral ischemia
hiv aids
cerebrospinal fluid
gene expression
dna methylation