Leptin, adiponectin, and their ratio as markers of insulin resistance and cardiometabolic risk in childhood obesity.

Christine Frithioff-Bøjsøe Morten Asp Vonsild LundUlrik Lausten-ThomsenPaula L HedleyOluf PedersenMichael ChristiansenJennifer L BakerTorben HansenJens-Christian Holm

Published in: Pediatric diabetes (2019)

Independent of the degree of obesity, leptin, adiponectin, and the L/A ratio were associated with insulin resistance and other cardiometabolic comorbidities in children with overweight/obesity, but the L/A ratio exhibited stronger associations than the respective adipokines.

Keyphrases

insulin resistance
metabolic syndrome
high fat diet induced

adipose tissue
high fat diet
skeletal muscle

polycystic ovary syndrome
type diabetes
weight loss

young adults
glycemic control
physical activity